Nitrogen Heterocyclic Photosensitizer

Professional Nitrogen Heterocyclic Photosensitizer Manufacturers!

 

Zhengzhou Yuanli Biological Technology Co., Ltd. Founded in 2009, it focuses on the technological development and achievement transformation of chemical APIs, new materials and new drugs. It's the supplier of BNCT treatment products. The company is also a leading research and development institution and product supplier of Nitrogen heterocyclic (Acridine) series and Boron cluster (Carborane) series.

 
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Why Choose Us

 

Our Factory
The R&D center is over 4,500㎡in Zhengzhou High tech Zone, and has a pilot plant, industrial transformation, and production base of over 80,000㎡in Sanmenxia Chemical Industry Park.

 

Quality Control
Our state-of-the-art facilities ensure compliance with regulatory standards, providing clients with reliable and efficient sourcing solutions. We manufacture your active pharmaceutical ingredients in compliance with the highest quality and safety standards.

 

Our Certificate
We provide products cooperation for customers in over 70 countries and have products or technology collaborations with over 80 universities or research institutions. Currently, 67 invention patents have been applied and 35 have been authorized. It's a National High-tech Enterprise company and also gets so many other certificates of provincial and city level.

Types of Nitrogen Heterocyclic Photosensitizer

We offer the following Product:

9(10H)-Acridone, 9-Acridone

9(10H)-Acridone, 9-Acridone, is a yellow powder, CAS: 578-95-0. Used for orgnic synthesis, pharmaceutical intermediates. Soluble in acetic acid, hot alcohol, potassium hydroxide and alcohol solution, insoluble in water, ether, benzene and chloroform. Emitted blue fluorescense in the alcohol solution.

9-Oxo-10(9H)-acridineacetic Acid

9-Oxo-10(9H)-acridineacetic acid, Acridone acetic acid, yellow to yellowish green crystalline powder, CAS: 38609-97-1. Used for pharmaceutical intermediates, HPLC derivatization reagents, progesterone receptor activators, and potential antibacterial, antifungal, and anti-tumor drug components.

99% Assay 9(10H)-Acridone, 9-Acridone, CAS: 578-95-0
99% Acridone Acetic Acid, 9-Oxo-10(9H)-acridineacetic Acid, CAS:38609-97-1

9-Phenylacridine, 9-Pa

9-Phenylacridine, 9-Pa, yellow or light yellow solid, CAS: 602-56-2, is an organic synthesis intermediates and material intermediates, used in laboratory research and industrial production.

Acridone Acetate Sodium, 2-(9-oxoacridin-10-yl)

Acridone Acetate Sodium, 2-(9-oxoacridin-10-yl)acetic acid, greenish-yellow finely crystalline powder, CAS: 58880-43-6. Acridone Acetate Sodium is a compound used for anti-cancer, treatment of herpes zoster, as a pharmaceutical intermediate, and as an antibiotic.

 

Product Specification

We offer the following Product specifications:

9(10H)-Acridone, 9-Acridone

Description

Crystal Powder from yellow to green-yellow color

Green-yellow powder

Identity

The retention time of the main peak in the chromatogram of the test solution for mass fraction of acridone should correspond to the retention time of the main peak of the solution of the standard sample of acridone.

Complies

Related Impurities by HPLC

Single impurities not more than 0.2%
Total amount of impurities no more than 1.0%

Complies

Mass fraction of Acridone

No less than 99%

99.90%

Loss of mass on drying

No more than 0.3%

0.03%

Mass fraction of Clorides

Not more than 0.1%

Complies

Mass fraction of Sulphate

Not more than 0.7%

Complies

Melting Point

361-366℃

Complies

9-Oxo-10(9H)-acridineacetic Acid

Appearance

Yellow to yellowish green crystalline powder

Complies

Melting point

>280℃

286.4-286.7℃

Loss on drying

≤0.5%

0.10%

Purity

≥99%

99.68%

Clarity

The sample solution should be clear and transparent, the color of the solution should not be darker than yellow green 7# color code.

Complies

Impurity

Acridone NMT 0.15%

0.067%

N-Methyl acridone NMT 0.1%

0.064%

Unidentified impurities NMT 0.1%

Complies

Sum of impurities NMT 0.5%

0.32%

Sulfuric ash

≤0.1%

0.03%

Heavy metals, lead

≤10ppm

Complies

Chlorides

≤0.01%

Complies

 

 

Applications of Nitrogen Heterocyclic Photosensitizer

01/

Nitrogen Heterocycles as Drugs
Nitrogen-containing heterocycles are amongst the most prominent structural entities of pharmaceuticals. As per U.S FDA pharmaceuticals, a detailed analysis of the N-heterocycles showed that 59% of small-molecule drugs possess nitrogen heterocycles, making them the most significant and privileged structures among heterocycles. The most notable ones incorporated as drugs contain piperazine, morphinan, cepham, penam, or phenothiazine moiety. A series of nitrogen heterocycles having distinguishable structural modifications being synthesized possess diverse biological activity.

02/

Nitrogen Heterocycles as Polymers
The ability of nitrogen heterocycles to bond with metals, act as ligands, to undergo hydrogen bonding with proteins and drugs has resulted in their utility as multifunctional polymers. These polymers have diverse applications. For example, hydrogels obtained via polymerized methylimidazolium-based ionic liquids have prominent bioactive applications as these polymers self-assemble into arranged lamella with distinct swelling properties. Nitrogen heterocycles afford many biophysical applications, and their polymers represent a new and comparatively unexplored field. The supra-molecular association of these biopolymers for various antimycotic and antimicrobial drug applications has recently been of keen interest.

03/

Nitrogen Heterocycles as Agrochemicals
Nitrogen heterocycles have arisen as one of the prominent agents for crop protection. Cutting-edge development in the synthesis and design of agrochemicals has formed the backbone of the agrochemical industry. More than 70% of the already introduced agrochemicals possess heterocyclic scaffolds primarily containing one or more nitrogen atoms. State-of-the-art organic chemistry used to manufacture advanced crop protection chemicals includes the production of three commercially available fungicides, boscalid, fludioxonil, and benomyl. Crop protection chemistry has occupied an important domain in organic chemistry as structure-based designs are needed to achieve the required targets.

04/

Nitrogen Heterocycles as Dyes
Heterocyclic compounds as dyes are still being utilized in traditional protocols, but these are also key constituents in fluorescent probes. These dyes show a promising paradigm shift in technology and are being implemented in solar cell technology, optoelectronics, photodynamic therapy, and photoinduced electron transfer imaging (PET). Nitrogen-bearing heterocycle dyes have varied applications in diverse fields like analytic chemistry, pharmaceuticals, textile, cosmetics, and leather.

 

Other Services

 

Packing
The goods is packaged in cardboard drums, inside double layer polyethylene bags, 25kg/Drum, also can be packaged according to customer requirements.

 

Handling and Transportation
Packaging is suitable for all modes of transportation such as express delivery, airplane, sea freight, etc.

 

Storage
The goods should be stored in a cool, dry, and well ventilated place, sealed. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels.Touch the package with water or any other liquid directly will cause the product to cake, should be stacked in pallets. Under normal conditions,the use of this product does not cause any undue health hazard. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.

 

Certification

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FAQ

Q: What are nitrogen heterocyclic compounds used for?

A: Nitrogen heterocycles have been found to mimic various endogenous metabolites and natural products, highlighting their pivotal role in current drug design. Their applications are manifold and are predominantly used as pharmaceuticals, corrosion inhibitors, polymers, agrochemicals, dyes, developers, etc.

Q: Why are nitrogen heterocycles important?

A: The N-heterocyclic skeletons feature significantly various classes of therapeutic applications and are used as the building blocks of a number of new drug candidates, due to the ability of the nitrogen atom to easily form hydrogen bonding with biological targets.

Q: What are the three nitrogen-containing heterocyclic compounds?

A: Nitrogen-containing heterocyclic compounds are cyclic compounds that consist of both carbon and nitrogen atoms. Examples of these compounds include pyrrole, imidazole, and pyrazole, all of which contain nitrogen heteroatoms.

Q: What is the use of acridone?

A: A lot of work had been carried out on the acridone nucleus due to its variety of pharmacological activities. These pharmacological activities include anticancer, antimicrobial, antiviral, antimalarial and anti-inflammatory activities.

Q: What are acridone derivatives?

A: An acridone derivative is a type of compound that is synthesized by modifying the acridone scaffold. In the context of ABCG2 inhibitors, acridone derivatives with specific methoxy group substitutions have been found to be essential for activity.

Q: What are derivatives in drugs?

A: A drug derivative refers to a modified form of a drug molecule that is linked to antibodies, resulting in potent and targeted therapeutic agents with improved stability and reduced toxicity compared to the original drug.

We're well-known as one of the leading nitrogen heterocyclic photosensitizer manufacturers and suppliers in China. Please feel free to buy high quality nitrogen heterocyclic photosensitizer at competitive price from our factory. Contact us for more details.

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