Zhengzhou Yuanli Biological Technology Co., Ltd. Founded in 2009, it focuses on the technological development and achievement transformation of chemical APIs, new materials and new drugs. It's the supplier of BNCT treatment products. The company is also a leading research and development institution and product supplier of Nitrogen heterocyclic (Acridine) series and Boron cluster (Carborane) series.
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Our Factory
The R&D center is over 4,500㎡in Zhengzhou High tech Zone, and has a pilot plant, industrial transformation, and production base of over 80,000㎡in Sanmenxia Chemical Industry Park.
Quality Control
Our state-of-the-art facilities ensure compliance with regulatory standards, providing clients with reliable and efficient sourcing solutions. We manufacture your active pharmaceutical ingredients in compliance with the highest quality and safety standards.
Our Certificate
We provide products cooperation for customers in over 70 countries and have products or technology collaborations with over 80 universities or research institutions. Currently, 67 invention patents have been applied and 35 have been authorized. It's a National High-tech Enterprise company and also gets so many other certificates of provincial and city level.
Intermediates for Overview
Pharmaceutical intermediates and chemical compounds are widely used in manufacturing various types of active pharmaceutical ingredients (APIs) in bulk quantity. They are also useful for research and development for new drug products.An intermediate or reaction intermediate is a substance formed during a middle step of a chemical reaction between reactants and the desired product. Intermediates tend to be extremely reactive and short-lived, so they represent a low concentration in a chemical reaction compared with the amount of reactants or products. Many intermediates are unstable ions or free radicals.
Types of Intermediates
We offer the following Product:
Uracil
Uracil is white crystalline power. It is used for pharmaceutical intermediates, is the main raw material for manufacturing fluorouracil. It is a raw material for the synthesis of compounds such as guanosine, and also plays an important role in organic synthesis.
Meglumine Powder
Meglumine, is white crystalline power, Meglumine can be used as a contrast agent and surfactant, also used for pharmaceutical excipients and intermediates.
1,4-Thioxane-1,1-dioxide
1,4-Thioxane-1,1-dioxide C4H8O3S, is white solid, uniform color without foreign matter, uniform particle size without cakingwhite. 1,4-Thioxane-1,1-dioxide is used for pharmaceutical intermediates.
Aloe Emodin Powder
Aloe emodin is light to dark orange powder. This product has antibacterial effects and inhibits multiple bacteria, including Staphylococcus, Streptococcus, Corynebacterium diphtheriae, Bacillus subtilis, Shigella, etc.
Advantages of Intermediates
Enabling Multi-Step Synthesis
Intermediates allow for gradual chemical changes, essential for creating APIs with precise molecular structures required for effective drugs.
Maintaining Quality and Consistency
Each intermediate must meet specific quality standards, preventing impurities and ensuring that the final API maintains consistent efficacy and safety.
Improving Production Efficiency
By dividing the synthesis into stages, intermediates help streamline production, allowing for early detection and correction of any issues, reducing overall costs and time.
Supporting Scalability
Intermediates enable large-scale production of APIs, ensuring reliable and consistent quality to meet high demand.
Enhancing Safety
Intermediates provide checkpoints for quality and impurity control, reducing risks and ensuring that the final API adheres to safety standards.
Product Specification
We offer the following Product specifications：
|
Uracil |
||
|
Appearance |
White or almost white crystalline powder |
Complies |
|
Melting point |
≥300.0℃ |
Complies |
|
Loss on drying |
≤0.5% |
0.1% |
|
Chloride |
≤0.01% |
Complies |
|
Sulfate |
≤0.04% |
Complies |
|
Residue on ignition |
≤0.10% |
0.05% |
|
Heavy metals |
≤0.001% |
Complies |
|
Assay |
≥99.5% |
99.9% |
|
Meglumine Powder |
||
|
Appearance |
White crystalline power |
White crystalline power |
|
Melting point |
128℃～132℃ |
129.2℃～130.9℃ |
|
Loss on drying |
≤0.5% |
0.05% |
|
Content |
≥99.0% |
99.50% |
|
Specific optical rotation |
﹣15.5º－﹣17.5º |
﹣16.2º |
|
Residue on ignition |
≤0.1% |
0.02% |
|
Heavy metals |
≤10ppm |
Complies |
|
Absence of reducing substance |
Blue don't change to red |
Complies |
|
Readily carbonizable substance |
No deeper than the orange red no.2 |
Complies |
|
Clarity of the solution |
Clear and colourless Solution |
Complies |
|
Ultraviolet absorbancy degree |
≤0.03 |
0.01 |
|
Nickel |
≤5ppm |
﹤3ppm |
|
1,4-Thioxane-1,1-dioxide |
||
|
Appearance |
White solid, uniform color without foreign matter, uniform particle size without caking |
Complies |
|
Identification |
The nuclear magnetic spectrum is consistent with the standard sample |
Complies |
|
Purity |
≥98% |
99.80% |
|
Water content |
≤0.5% |
0.09% |
|
Any single impurity |
≤0.5% |
Complies |
|
Melting point |
131-134℃ |
131.4-132.0°C |
Other Services
Packing
The goods is packaged in cardboard drums, inside double layer polyethylene bags, 25kg/Drum, also can be packaged according to customer requirements.
Handling and Transportation
Packaging is suitable for all modes of transportation such as express delivery, airplane, sea freight, etc.
Storage
The goods should be stored in a cool, dry, and well ventilated place, sealed. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels.Touch the package with water or any other liquid directly will cause the product to cake, should be stacked in pallets. Under normal conditions,the use of this product does not cause any undue health hazard. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.
Certification
FAQ
We're well-known as one of the leading intermediates manufacturers and suppliers in China. Please feel free to buy high quality intermediates at competitive price from our factory. Contact us for more details.
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