Zhengzhou Yuanli Biological Technology Co., Ltd. Founded in 2009, it focuses on the technological development and achievement transformation of chemical APIs, new materials and new drugs. It's the supplier of BNCT treatment products. The company is also a leading research and development institution and product supplier of Nitrogen heterocyclic (Acridine) series and Boron cluster (Carborane) series.
Our Factory
The R&D center is over 4,500㎡in Zhengzhou High tech Zone, and has a pilot plant, industrial transformation, and production base of over 80,000㎡in Sanmenxia Chemical Industry Park.
Quality Control
Our state-of-the-art facilities ensure compliance with regulatory standards, providing clients with reliable and efficient sourcing solutions. We manufacture your active pharmaceutical ingredients in compliance with the highest quality and safety standards.
Our Certificate
We provide products cooperation for customers in over 70 countries and have products or technology collaborations with over 80 universities or research institutions. Currently, 67 invention patents have been applied and 35 have been authorized. It's a National High-tech Enterprise company and also gets so many other certificates of provincial and city level.
Boron Cluster Compounds Overview
Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical drugs. The boron-containing compounds epitomize a new class for medicinal chemists to use in their drug designs. Carboranes are a class of organometallic compounds containing carbon (C), boron (B), and hydrogen (H) and are the most widely studied boron compounds in medicinal chemistry.
Types of Boron Cluster Compounds
We offer the following Product:
O-Carborane Powder
O-Carborane is white or yellowish powder. o-Carborane can be used in semiconductors, neutron detection, and photocatalysts BNCT, Solid fuel additives, material intermediates.
Top Purity M-Carborane, Meta-Carborane
M-Carborane is light yellow to white crystals. It is mainly used in the fields of medicine, aviation, and chemical synthesis. Aradiation sensitizer raw material for BNCT, used for preparing semiconductor composite films through plasma enhanced chemical reactions, synthesizing cross-linked benzocyclobutene resins with meta carborane and siloxane skeletons, rocket solid propellants, and reducing agents.
P-Carborane, Para-Carborane
P-Carborane C2H12B10, CAS: 20644-12-6,is white solid. It is used as a radiosensitizer material for BNCT, for tumor imaging and cancer treatment. It can also be used for modifying adhesives, ceramic precursors, and semiconductor boron carbide films.
1-Bromomethyl-o-carborane
1-Bromomethyl-o-carborane C3B10H13Br, CAS: 19496-84-5，is colorless to light yellow crystals or liquid. 1-Bromomethyl-o-carborane is used as catalyst, initiator, material, medical, pharmaceutical chemistry, and intermediate in material chemistry.
Product Specification
We offer the following Product specifications：
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O-Carborane Powder |
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Test Items |
Requirements |
Results |
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Appearance |
White or yellowish powder |
White powder |
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Clarity |
No more than No.3 turbidity |
Complies |
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Assay |
≥98.0% |
99.87% |
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M-Carborane, Meta-Carborane |
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Test Items |
Requirements |
Results |
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Appearance |
Light yellow to white crystals |
White crystal |
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Assay |
≥97.0% |
98.49% |
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P-Carborane, Para-Carborane |
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1-Bromomethyl-o-carborane |
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Test Items |
Requirements |
Results |
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Appearance |
White solid |
White solid |
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Assay |
≥98.0% |
99.81% |
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Test Items |
Requirements |
Results |
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Appearance |
Colorless to light yellow crystals or liquid |
Complies |
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Melting point |
30～34℃ |
30.3～31.0℃ |
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Assay |
≥95.0% |
99.25% |
Chemistry Properties of Boron Cluster Compounds
Dicarba-carboranes
For o-carborane, a well-developed chemistry is available for functionalization at the C atoms, and at any of the B atoms. This is not so for the two other isomers, m- and p-carborane. Here, the available reactions described are limited, which might hinder considerably their incorporation into drugs.
Monocarba-Carboranes
For the CB11 cluster, methods for C-functionalization are well-known. Functionalization at the B atom in para-position to the C atom and a few other modification reactions are described, but the possibilities for functionalization are still limited.
Dodecaborates
B12H122- is readily mono-substituted with oxygen (especially through oxonium ions), nitrogen (hydroxylamine-O-sulfonic acid) and halogens (through elemental halogens). Methods for direct introduction of carbon substituents are not readily available, but the cross-coupling reaction of monoiodo-dodecaborate with Grignard reagents is a useful reaction. Microwave mediation increases the yields of such reactions (including those with oxonium derivatives) considerably.
Other Services
Packing
The goods is packaged in cardboard drums, inside double layer polyethylene bags, 25kg/Drum, also can be packaged according to customer requirements.
Handling and Transportation
Packaging is suitable for all modes of transportation such as express delivery, airplane, sea freight, etc.
Storage
The goods should be stored in a cool, dry, and well ventilated place, sealed. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels.Touch the package with water or any other liquid directly will cause the product to cake, should be stacked in pallets. Under normal conditions,the use of this product does not cause any undue health hazard. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.
Certification
FAQ
We're well-known as one of the leading boron cluster compounds manufacturers and suppliers in China. Please feel free to buy high quality boron cluster compounds at competitive price from our factory. Contact us for more details.
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